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Nihon Kyobu Shikkan Gakkai Zasshi · May 1994
Case Reports[A case of drug induced pneumonitis caused by saiboku-To].
- R Temaru, N Yamashita, S Matsui, T Ohta, A Kawasaki, and M Kobayashi.
- Department of Internal Medicine, Toyama Prefecture Saisei Kai Takaoka Hospital, Japan.
- Nihon Kyobu Shikkan Gakkai Zasshi. 1994 May 1; 32 (5): 485-90.
AbstractWe report a case of drug induced pneumonitis caused by Saiboku-To. A 60-year-old woman was admitted to our hospital because of dry cough, fever and severe dyspnea after taking Saiboku-To. Blood gas analysis showed marked hypoxemia. Chest X-ray obtained on admission showed diffuse ground glass shadows in bilateral lung fields, and computed tomography showed diffuse interstitial shadows. Following steroid pulse therapy, clinical symptoms, hypoxemia and chest X-ray findings were ameliorated. Against medical advice, she took another Chinese medicine with ingredients similar to those of Saiboku-To. She complained of dry cough, fever and dyspnea and the chest X-ray again revealed diffuse ground glass shadows in both lung fields. Lymphocyte stimulation test against Saiboku-To and the patch test for Saiboku-To were positive. Therefore, we diagnosed this case as having pneumonitis due to Saiboku-To. This is first report of interstitial pneumonitis due to Saiboku-To.
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