Nihon Kyōbu Shikkan Gakkai zasshi
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Nihon Kyobu Shikkan Gakkai Zasshi · May 1994
Case Reports[A case of drug induced pneumonitis caused by saiboku-To].
We report a case of drug induced pneumonitis caused by Saiboku-To. A 60-year-old woman was admitted to our hospital because of dry cough, fever and severe dyspnea after taking Saiboku-To. Blood gas analysis showed marked hypoxemia. ⋯ Lymphocyte stimulation test against Saiboku-To and the patch test for Saiboku-To were positive. Therefore, we diagnosed this case as having pneumonitis due to Saiboku-To. This is first report of interstitial pneumonitis due to Saiboku-To.
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Nihon Kyobu Shikkan Gakkai Zasshi · May 1994
Case Reports[A case of eosinophilic pneumonia caused by inhalation of nickel dusts].
A 16-year-old male, an industrial high school student working at an ironworks, without a dust mask, began to complain of dry cough and fever several hours after inhalation of stainless steel dusts including 0.1% nickel. A chest X-ray film revealed ground glass shadows, patchy shadows and Kerley B lines in the right lung fields. A high resolution chest CT scan showed fusing panlobular densities, thickening of bronchial walls and thickening of interlobular septa. ⋯ The positive results of the inhalation provocation test provided a definite diagnosis of nickel induced eosinophilic pneumonia. A review of the world literature revealed three case reports of nickel induced PIE syndrome, all of whom were clinically diagnosed without biopsy however. We believe that this is the first case diagnosed by transbronchial biopsy-proven tissue eosinophilia and a positive nickel inhalation provocation test.