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- Thomas Grüning, Brent E Drake, Sally L Farrell, and Tim Nokes.
- Department of Nuclear Medicine, Derriford Hospital, Plymouth, United Kingdom. Electronic address: thomas.gruning@nhs.net.
- Clin Imaging. 2014 Nov 1; 38 (6): 831-5.
AbstractVentilation-perfusion (VQ) single-photon emission computed tomography (SPECT) comprised the administration of SmartVent (n=386) or Technegas (n=1564) and 200 MBq (99m)Tc-MAA. 1406 scans were normal, 462 showed PE, 61 showed a singular subsegmental mismatched defect, 21 scans were non-diagnostic. 26% of scans performed with Technegas showed PE, compared to 15% with SmartVent. VQ SPECT had a sensitivity of 95.7%, specificity 98.6%, positive predictive value 95.7%, negative predictive value 98.6%. A normal VQ SPECT scan implied a more than ten-fold lower cause-specific mortality (1 in 1406) than a scan showing PE (1 in 116). NPV of a negative D-dimer was 94.3%. Copyright © 2014 Elsevier Inc. All rights reserved.
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