• Pediatric radiology · Oct 2017

    Observational Study

    The value of postmortem computed tomography in paediatric natural cause of death: a Dutch observational study.

    • Rick R van Rijn, Erik J Beek, Elise M van de Putte, Arianne H Teeuw, Nikkels Peter G J PGJ Department of Pathology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, the Netherlands., Wilma L J M Duijst, Nievelstein Rutger-Jan A RA Department of Radiology, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, the Netherlands., and Dutch NODO Group.
    • Department of Radiology, Emma Children's Hospital, Academic Medical Centre Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam Zuid-Oost, the Netherlands. r.r.vanrijn@amc.uva.nl.
    • Pediatr Radiol. 2017 Oct 1; 47 (11): 1514-1522.

    BackgroundPostmortem CT is a relatively new field of interest within paediatric radiology. This paper focusses on its value in cases of unexpected natural death.ObjectiveWe report on an observational Dutch study regarding the value of postmortem CT in children with an assumed natural unexpected death because postmortem CT is part of the Dutch NODO (additional investigations of cause of death) procedure.Materials And MethodsWe included consecutive children who fulfilled criteria for the NODO procedure and were therefore referred to one of the centres for the procedure. Postmortem CT was performed in all cases and skeletal survey was performed in all children ages <5 years. The cause of death was defined in a consensus meeting.ResultsWe included a total of 54 children (30 boys, median age 1.1 years, and 24 girls, median age 0.8 years). A definitive cause of death was established in 38 cases. In 7 cases the cause of death could be identified on postmortem CT. In 7 cases imaging findings were clinically relevant but did not lead to a cause of death. In the remaining 40 cases postmortem CT did not add to the diagnostic workup.ConclusionOur study shows that in a group of children who unexpectedly died of an assumed natural cause of death and in whom a cause of death was found at autopsy, postmortem CT detected the cause of death in a minority of cases (12.9%). In the majority of cases (74.1%) postmortem CT did not add value in diagnosing the cause of death.

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