• Brit J Hosp Med · Jul 2015

    Review

    Early phase cancer clinical trials: design, ethics and future directions.

    • Nicholas Coupe, Avinash Gupta, and Simon R Lord.
    • Clinical Research Fellow in Medical Oncology.
    • Brit J Hosp Med. 2015 Jul 1; 76 (7): 409-13.

    AbstractThe main role of early phase clinical trials in cancer is to determine the dose to take forward for future clinical study. However, study design is changing in order to account for the change in focus of drug development toward molecularly targeted agents.

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