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- Omer Gendelman, Yuval Kuntzman, Ora Shovman, Pnina Langevitz, Avishai M Tsur, Daniel Erez, Yair Levy, and Howard Amital.
- Department of Medicine B, Sheba Medical Center, Tel Hashomer, Israel.
- Isr Med Assoc J. 2021 Jun 1; 23 (6): 350-352.
BackgroundGranulomatosis with polyangiitis (GPA) is a rare small vessel vasculitis. It usually involves the respiratory tract and kidney. Rarely, tumor-resembling inflammatory changes ensue.ObjectivesTo report three unique cases of GPA presenting with tumor-like lesions in various organs.MethodsWe presented three cases of GPA. Case 1 presented with typical upper respiratory symptoms of GPA and a mediastinal mass. Case 2 presented with low back pain, a large retroperitoneal mass, and nodular skin lesions. Case 3 presented with epigastric pain and a paravertebral inflammatory mass.ResultsThe patients were treated successfully with rituximab.ConclusionsClinicians should be aware of this presentation of granulomatosis with polyangiitis, which is known as Tumefaction Wegener's granulomatosis.
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