Sporotrichosis refractory to conventional treatment:

An Bras Dermatol · Mar 2021

Case Reports

Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide.

Sporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. ⋯ This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient.

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- Marcelo Rosandiski Lyra, Vanessa Sokoloski, de Macedo Priscila Marques PM Instituto Nacional de Infectologia Evandro Cha... more
- Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. Electronic address: marcelo.lyra@ini.fiocruz.br.
- An Bras Dermatol. 2021 Mar 1; 96 (2): 231-233.
AbstractSporotrichosis is a subcutaneous mycosis caused by dimorphic fungi of the genus Sporothrix. The authors report a case of fixed cutaneous sporotrichosis with therapeutic failure after 18 months of itraconazole and terbinafine associated with cryosurgery. The patient was cured after the introduction of saturated potassium iodide solution. Sporothrix brasiliensis was the identified species, presenting a susceptibility profile to itraconazole and terbinafine. This fact suggests that therapeutic failure is probably related to the host-fungus interaction rather than drug resistance. It is possible that the immunomodulatory action of the saturated potassium iodide solution may have played an important role in curing this patient.Copyright © 2021 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.

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Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide.

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Sporotrichosis refractory to conventional treatment: therapeutic success with potassium iodide.

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