• J Laloze, A Varin, N Bertheuil, J L Grolleau, C Vaysse, and B Chaput.
• Department of Plastic, Reconstructive and Aesthetic Surgery, Rangueil Hospital, 1, avenue Jean-Poulhès, 31059 Toulouse, France; STROMAlab, Université de Toulouse, EFS, ENVT, INSERM U1031, Toulouse, France.
• Ann Chir Plast Esthet. 2017 Dec 1; 62 (6): 609-616.

AbstractAutologous fat transfer, or lipofilling, is a common technique used for soft tissue reconstruction. It has been used for many years, but the technique is associated with a significant graft resorption rate (20% to 80%). To improve the fat graft survival rate, several methods have been tested, and one has appeared more promising: cell-assisted lipotransfer (CAL). In the CAL method, fat is enriched with adipose-derived stromal cells (ASC), contained in the stromal vascular fraction (SVF) obtained after enzymatic digestion of fat or after cell culture to improve the fat survival rate. In this concise review, we present the clinical indications, and the technical principles of CAL, as well as a presentation of ASC. To conclude, we present the main results (efficacy, complications and safety) obtained from different studies of this technique.Copyright © 2017 Elsevier Masson SAS. All rights reserved.

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