• Ocul. Immunol. Inflamm. · Nov 2020

    Review

    SARS-CoV-2 Targeting the Retina: Host-virus Interaction and Possible Mechanisms of Viral Tropism.

    • Camila Saggioro de Figueiredo, Ícaro Raony, and Elizabeth Giestal-de-Araujo.
    • Department of Neurobiology, Program of Neurosciences, Federal Fluminense University , Niterói, Brazil.
    • Ocul. Immunol. Inflamm. 2020 Nov 16; 28 (8): 1301-1304.

    AbstractBackground: Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 10 (SARS-CoV-2). Recent studies demonstrated not only retinal impairments but also detected SARS-CoV-2 in the retina of patients with COVID-19. Purpose: This letter discusses the retinal tropism of SARS-CoV-2, describing possible routes for this coronavirus to reach the retina and cellular mechanisms involved in the retinal cell infection. Conclusions: Determining how SARS-CoV-2 can affect the retinal tissue is essential for the development of new therapeutic strategies and preventive measures, as well as for understanding the possible relationship between COVID-19 damage to the retina and to the brain.

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