• Hye-Suk Hong, Hua Sun Kim, Myeong-Jin Kim, Jan De Becker, Donald G Mitchell, and Masayuki Kanematsu.
• Department of Diagnostic Radiology, Yonsei University College of Medicine, Research Institute of Radiological Science, Severance Hospital, Seoul, Republic of Korea.
• J Magn Reson Imaging. 2008 Aug 1; 28 (2): 396-402.

PurposeTo evaluate the feasibility of single breath-hold, multiarterial MRI of the liver using the THRIVE-CENTRA-keyhole technique.Materials And MethodsTwenty-eight patients with 63 focal hepatic lesions underwent liver MR examinations that included the three-dimensional THRIVE-CENTRA-keyhole sequence. Three or six phases were obtained for arterial phase scanning during a single breath-hold. Central k-space data were collected for each phase but the remaining peripheral k-space data were collected only once. The enhancement pattern of each hepatic lesion was analyzed according to the specific diagnosis.ResultsHepatocellular carcinomas (n = 24) enhancement patterns included: rim enhancing (n = 9), homogeneous (n = 7), nodule-in-nodule (n = 5), or heterogeneous (n = 3). A late peritumoral rim was observed in four (17%) of the hepatocellular carcinomas. Most metastases (17 of 18; 94%) demonstrated peripheral rim enhancement. The progressive centripetal enhancement of hemangiomas (n = 6) was clearly depicted. Focal nodular hyperplasia (n = 4) showed early homogeneous enhancement and one lesion demonstrated a central scar.ConclusionThe THRIVE-CENTRA-keyhole technique can be used to acquire single breath-hold, multiarterial images depicting improved enhancement characteristics of focal hepatic lesions. This technique will allow accurate timing of arterial scanning with 3D acquisition and high temporal resolution.(c) 2008 Wiley-Liss, Inc.

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