Journal of magnetic resonance imaging : JMRI
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J Magn Reson Imaging · Aug 2008
Comparative StudyComparison of T(1) and T(2) metabolite relaxation times in glioma and normal brain at 3T.
To measure T(1) and T(2) relaxation times of metabolites in glioma patients at 3T and to investigate how these values influence the observed metabolite levels. ⋯ The differential increase in T(2) for Cho and Cr relative to NAA means that the ratios of Cho/NAA and Cr/NAA are higher in tumor at longer echo times (TEs) relative to values in normal appearing brain. Having this information may be useful in defining the acquisition parameters for optimizing contrast between tumor and normal tissue in MR spectroscopic imaging (MRSI) data, in which limited time is available and only one TE can be used.
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J Magn Reson Imaging · Aug 2008
Comparative StudyMonitoring of early response to neoadjuvant chemotherapy in breast cancer with (1)H MR spectroscopy: comparison to sequential 2-[18F]-fluorodeoxyglucose positron emission tomography.
To assess the efficacy of (1)H MR spectroscopy (MRS) to evaluate early responses to neoadjuvant chemotherapy in breast cancer patients, as compared to that of the standardized uptake value (SUV) in (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET). ⋯ A change in the Cho integral value is well correlated with that of peak SUV in the time course of neoadjuvant chemotherapy; thus, breast (1)H MRS is thought to be an alternative to sequential (18)F-FDG PET.
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J Magn Reson Imaging · Aug 2008
Automatic correction of intensity inhomogeneities improves unsupervised assessment of abdominal fat by MRI.
To demonstrate that unsupervised assessment of abdominal adipose tissue distribution by magnetic resonance imaging (MRI) can be improved by integrating automatic correction of signal inhomogeneities. ⋯ The results of this study suggest that the compensation of signal inhomogeneities greatly improves the effectiveness of the unsupervised assessment of abdominal fat. Correction of intensity distortions is important in SAT evaluation and less significant in VAT measurement.
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J Magn Reson Imaging · Aug 2008
Comparative StudyMRI vs. ultrasound for suspected appendicitis during pregnancy.
To compare the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of ultrasound (US) and MRI in evaluation of pregnant patients with a clinical suspicion of appendicitis. ⋯ Based on a relatively small number of true-positives, our data suggests that MRI is very useful for the diagnosis and exclusion of appendicitis in pregnant women.
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J Magn Reson Imaging · Aug 2008
Single breath-hold multiarterial dynamic MRI of the liver at 3T using a 3D fat-suppressed keyhole technique.
To evaluate the feasibility of single breath-hold, multiarterial MRI of the liver using the THRIVE-CENTRA-keyhole technique. ⋯ The THRIVE-CENTRA-keyhole technique can be used to acquire single breath-hold, multiarterial images depicting improved enhancement characteristics of focal hepatic lesions. This technique will allow accurate timing of arterial scanning with 3D acquisition and high temporal resolution.