• Acta radiologica · Jul 2007

    Comparative Study Clinical Trial

    Assessment of 3D-TOF-MRA at 3.0 Tesla in the characterization of the angioarchitecture of cerebral arteriovenous malformations: a preliminary study.

    • J O Heidenreich, A M Schilling, F Unterharnscheidt, R Stendel, S Hartlieb, F K Wacker, P Schlattmann, K-J Wolf, and H Bruhn.
    • Department of Radiology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio 44106-5000, USA. jens.heidenreich@case.edu
    • Acta Radiol. 2007 Jul 1; 48 (6): 678-86.

    BackgroundThe characterization of brain arteriovenous malformation (AVM) angioarchitecture remains rewarding in planning and predicting therapy. The increased signal-to-noise ratio at higher field strength has been found advantageous in vascular brain pathologies.PurposeTo evaluate whether 3.0T time-of-flight (TOF) magnetic resonance angiography (MRA) is superior to 1.5T TOF-MRA for the characterization of cerebral AVMs.Material And MethodsFifteen patients with AVM underwent TOF-MRA at 3.0T and 1.5T and catheter angiography (DSA), which was used as the gold standard. Blinded readers scored image quality on a four-point scale, nidus size, and number of feeding arteries and draining veins.ResultsImage quality of TOF-MRA at 3.0T was superior to 1.5T but still inferior to DSA. Evaluation of nidus size was equally good at 3.0T and 1.5T for all AVMs. In small AVMs, however, there was a tendency of size overestimation at 3.0T. MRA at 3.0T had increased detection rates for feeding arteries (+21%) and superficial (+13%) and deep draining veins (+33%) over 1.5T MRA.Conclusion3.0T TOF-MRA offers superior characterization of AVM angioarchitecture compared with 1.5T TOF-MRA. The image quality of MRA at both 3.0 and 1.5T is still far from equal to DSA, which remains the gold standard for characterization of AVM.

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