• Dermatologic clinics · Jul 1992

    Review

    Oculocutaneous manifestations of the erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum.

    • J Wilkins, L Morrison, and C R White.
    • Department of Ophthalmology, Oregon Health Sciences University, Portland.
    • Dermatol Clin. 1992 Jul 1; 10 (3): 571-82.

    AbstractAlthough they were once believed to be distinct diseases, many observers currently consider erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis to represent a mild-to-severe continuum of the same process. Each shares certain clinical, histologic, and etiologic characteristics; among the latter two are frequent ocular involvement. Because long-term ophthalmic sequelae may be catastrophic, early recognition and therapy of this acute oculocutaneous disease spectrum are critically important.

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