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J. Pediatr. Hematol. Oncol. · Nov 2010
Review Case ReportsTreatment of Gorham-Stout disease with zoledronic acid and interferon-α: a case report and literature review.
- Dawn K Kuriyama, Sean C McElligott, Darryl W Glaser, and Karen S Thompson.
- Family Medicine Residency, University of Hawaii, Honolulu, HI, USA.
- J. Pediatr. Hematol. Oncol. 2010 Nov 1; 32 (8): 579-84.
AbstractGorham-Stout disease is a rare disease characterized by osteolysis, angiomatosis, and soft-tissue swelling. It is a diagnosis of exclusion and has an unknown etiology. Chylothorax is a common complication of the disease that is associated with a high mortality rate. There is no standard of treatment. We report a case of a 16-year-old female with Gorham-Stout disease and recurrent pleural effusions who was successfully treated with concurrent zoledronic acid and peg-interferon α-2b.
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