• Gac Med Mex · Jan 2021

    Mexican Consensus on Hodgkin's Lymphoma.

    • José L Álvarez-Vera, Jocelyn Aguilar-Luevano, Luisa M Alcívar-Cedeño, Luara L Arana-Luna, Luis Arteaga-Ortiz, Pamela E Báez-Islas, Ana Carolina-Reynoso, Gabriela Cesarman-Maus, José A De la Peña-Celaya, María E Espitia-Ríos, Denisse J Fermín-Caminero, Willy Flores-Patricio, Alinka S García-Camacho, Pedro G Guzmán-Mora, Ana K Hernández-Colín, Eleazar Hernández-Ruiz, Wilfrido Herrera-Olivares, Elvia Jacobo-Medrano, Sergio J Loera-Fragoso, Juan P Macías-Flores, Mario A Martínez-Ramírez, Liliana Medina-Guzmán, Andrea I Milán-Salvatierra, Leire Montoya-Jiménez, Javier de J Morales-Adrián, Aldo Mujica-Martínez, Lorena Nava-Villegas, Juan J Orellana-Garibay, Orlando G Palma-Moreno, Juan M Pérez-Zúñiga, Karen D Pérez-Gómez, Yayra M Pichardo-Cepín, Flavio Rojas-Castillejos, Eduardo Romero-Martínez, Hilda Romero-Rodelo, Adela Segura-García, Karina Silva-Vera, Ana L Tapía-Enríquez, Óscar Teomitzi-Sánchez, Fredy Tepepa-Flores, Shendel P Vilchis-González, Atenas Villela-Peña, Lidia V Guerra-Alarcón, Rodrigo Reséndiz-Olea, Luisa Banda-García, Eugenia P Paredes-Lozano, and Martha Alvarado-Ibarra.
    • Servicio de Hematología, Centro Médico Nacional 20 de noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Ciudad de México.
    • Gac Med Mex. 2021 Jan 1; 157 (Supl 2): S1-S18.

    AbstractHodgkin's lymphoma is due to the clonal transformation of cells originating from B lymphocytes, generating the pathognomonic binucleate Reed-Sternberg cells. Hodgkin's lymphoma is a B cell disease with a bimodal distribution, with higher incidence in adolescence and the third decade of life, showing a second peak in people over 55 years of age. Classic Hodgkin lymphoma cells routinely undergo gene expression reprogramming, as they lose the expression of most of the typical B-cell genes and acquire the expression of multiple genes that are typical of other types of cells in the immune system. The treatment algorithm will depend on whether it is classic or predominantly lymphocytic HL, if it is early stage with unfavorable prognostic markers or not, the initial management regimen, and whether there is bulky disease, among the most relevant variables.Copyright: © 2021 Permanyer.

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