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- Yutaka Tokuda, Yuki Saito, Yasuhiro Suzuki, Masatoshi Ohta, and Tomoo Tajima.
- Department of Breast and Endocrine Surgery, Tokai University School of Medicine.
- Nippon Rinsho. 2002 Mar 1; 60 (3): 563-9.
AbstractThe HER2/neu protein is thought to be a unique and useful target for antibody therapy of cancers overexpressing the HER2/neu gene. The recombinant humanized anti-HER2 monoclonal antibody, trastuzumab(Herceptin) has recently been available for clinical use in Japan. In this paper, the details of this novel biologic agent are reviewed in conjunction with the results of the clinical trials for breast cancer.
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