• Hematol. Oncol. Clin. North Am. · Oct 2014

    Review

    Treatment of transplant-eligible patients with multiple myeloma in 2014.

    • Heather Landau and Sergio Giralt.
    • Adult BMT Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Weill Cornell Medical College, New York, NY 10065, USA.
    • Hematol. Oncol. Clin. North Am. 2014 Oct 1; 28 (5): 815-27.

    AbstractInduction regimens containing a proteasome inhibitor and/or immunomodulatory agent with dexamethasone result in rapid disease control before autologous stem cell transplantation (ASCT). ASCT followed by consolidation and/or maintenance further improves depth of response following effective induction. Overall survival of transplant-eligible patients has been extended with modern therapeutic strategies. The optimal timing of ASCT and methods to prevent relapse following ASCT are under active investigation. Different patient populations may benefit differentially from currently available treatments. Copyright © 2014 Elsevier Inc. All rights reserved.

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