• Jesús Antonio Viana-Rojas, Alejandro Rosas-Cabral, Jorge Prieto-Macías, Ma Carmen Terrones-Saldívar, Patricia Arcos-Noguez, Julieta Bermúdez-Gómez, Lidia Estephanie Martínez-Padilla, Darío Alejandro Sandoval-Valdez, Flavio Hernández-González, and Leopoldo César Serrano-Díaz.
• Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Aguascalientes, México. drrosascabral@gmail.com.
• Rev Med Inst Mex Seguro Soc. 2017 Mar 1; 55 (2): 176-181.

BackgroundIt has been established a strong association between the red cell distribution width (RDW) and mean platelet volume (MPV) with hypertension in non-pregnant patients. However, few studies have been performed in patients with preeclampsia, yielding inconsistent results. Our aim is to evaluate the relationship between RDW and MPV with the severity of preeclampsia.MethodsAnalytic cross-sectional study. We include 64 patients with preeclampsia (26 mild, 38 severe) and 70 patients with normotensive pregnancy. Clinical data, sociodemographic characteristics and laboratory measures, including RDW and MPV, were recorded for each patient.ResultsHemoglobin and platelet count measures were similar between groups. Preeclamptic patients had levels of RDW (14.7 ± 1.4 vs. 13.4 ± 0.7, p = 0.0001) and MPV (11.8 ± 2.4 vs. 11.0 ± 1.4, p = 0.03) more elevated than control group. Moreover, severe preeclamptic subgroup had more elevated levels of RDW (15.0 ± 1.6 vs. 14.0 ± 0.6, p = 0.001) and MPV (12.7 ± 2.8 vs. 10.8 ± 1.8, p = 0.01) in comparison with mild preeclamptic patients.ConclusionsWe demonstrate that RDW and MPV are accessible and inexpensive measures associated with the severity of preeclampsia.

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