• Journal of anesthesia · Jun 2013

    Case Reports

    Severe intraoperative hypertension after induction of anesthesia in a child with a neuroblastoma.

    • Hiromi Kako, Thomas Taghon, Giorgio Veneziano, Jennifer H Aldrink, Rose Ayoob, and Joseph D Tobias.
    • Departments of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA. Hiromi.Kako@nationwidechildrens.org
    • J Anesth. 2013 Jun 1; 27 (3): 464-7.

    AbstractNeuroblastomas are the most common, non-central nervous system tumor of childhood. Similar to pheochromocytomas, they are derived from neural crest cells and therefore retain the potential to synthesize catecholamines. Unlike pheochromocytomas, however, perioperative issues related to blood pressure instability with hypertension are uncommon. We report details of a 3-year-old child with a neuroblastoma who developed severe hypertension and end-organ effects after induction of anesthesia. The association of such problems with neuroblastoma is reviewed and options for perioperative care presented.

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