• Acta clinica Croatica · Jun 2020

    Review Case Reports

    Surgical Treatment of Recurrent Metastatic Parathyroid Gland Carcinoma.

    • Zaviša Čolović, Mladen Krnić, Zlatko Kljajić, Mirko Kontić, Nikola Kolja Poljak, Robert Tafra, and Petar Ivanišević.
    • 1University of Split, Split University Hospital Center, Department of Otorhinolaryngology, Split, Croatia; 2University of Split, Split University Hospital Center, Department of Endocrinology, Split, Croatia.
    • Acta Clin Croat. 2020 Jun 1; 59 (Suppl 1): 96-101.

    AimWe present the case of a 48-year-old male patient who underwent surgery for a recurrent metastatic parathyroid gland carcinoma in the patient's right paratracheal space of the neck. The patient had undergone surgery for lower right parathyroid gland carcinoma 28 months earlier.ResultsThe metastases were resected en bloc with an ipsilateral central neck dissection and with the removal of the enlarged lower left parathyroid gland. After exploration of the remnant parathyroid glands we noticed that lower left parathyroid gland was macroscopically enlarged so we decided to remove it to prevent possible hypercalcemia in future and to also prevent possible recurrence of cancer or development of a new primary, considering the identical embryological origin of the lower parathyroid glands and possibility of synchronous, multiple tumors, which generally follow the same embryological origin if they occur. The patient was also treated with radiation therapy after the surgery.ConclusionWith the present surgical approach to recurrent metastatic parathyroid gland carcinoma, we aimed to prevent the recurrence of cancer or development of new primary and prevent or delay hypercalcemia in the future with all severe adverse metabolic states associated with high serum calcium levels.

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