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- J Kühl.
- Paediatric Oncology/Haematology Section, Children's Hospital, University of Würzburg, Germany. kuehl@rzkli.uni-wuerzburg.de
- Childs Nerv Syst. 1998 Jan 1; 14 (1-2): 2-5.
AbstractChemotherapy has an important role in the modern treatment of children with medulloblastoma (MB). In patients at high risk, intense chemotherapy should improve the survival rate. In low-risk patients chemotherapy should allow the dose of craniospinal irradiation to be reduced, which in turn should improve the quality of life. In infants under 3 years of age radiotherapy should be delayed, or even replaced by postoperative chemotherapy. Chemotherapy is also necessary to prevent or treat systemic dissemination. The optimal timing of chemotherapy is a focus of contemporary research.
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