• Kim A Connelly, Jay S Detsky, John J Graham, Gideon Paul, Ram Vijayaragavan, Alexander J Dick, and Graham A Wright.
• Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. connellyk@smh.toronto.on.ca
• J Magn Reson Imaging. 2009 Oct 1; 30 (4): 771-7.

PurposeTo determine the accuracy of multicontrast late enhancement imaging (MCLE) in the assessment of myocardial viability and wall motion compared to the conventional wall motion and viability cardiac magnetic resonance imaging (MRI) pulse sequences.Materials And MethodsForty-one patients with suspected myocardial infarction were studied. Patients underwent assessment of cardiac function with cine steady-state free-precession (SSFP), followed by late gadolinium enhancement (LGE) imaging using inversion recovery gradient echo scanning (IR-GRE) sequence and MCLE. MCLE was compared to cine SSFP in the assessment of wall motion, ejection fraction (EF), left ventricular (LV) mass, LV end-diastolic volume (EDV), and to IR-GRE for measuring infarct size.ResultsMCLE, IR-GRE, and SSFP imaging demonstrated excellent agreement in the assessment of EF, LV infarct size, and LV mass (r > 0.95, P < 0.001 for all measures), as well as in the assessment of wall motion (kappa statistic 0.75).ConclusionMCLE provided coregistered images for the assessment of viability and wall motion without loss of accuracy in the assessment of quantitative cardiac parameters. MCLE provides accurate quantitative cardiac assessment with reduced scan times compared to the conventional sequences and thus may be used as an alternative to conventional cine SSFP and IR-GRE imaging.(c) 2009 Wiley-Liss, Inc.

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