• Nutr Hosp · Aug 2015

    Randomized Controlled Trial Clinical Trial

    ORGANIC INFLAMMATORY RESPONSE TO REDUCED PREOPERATIVE FASTING TIME, WITH A CARBOHYDRATE AND PROTEIN ENRICHED SOLUTION; A RANDOMIZED TRIAL.

    • Guilherme de Andrade Gagheggi Ravanini, Pedro Eder Portari Filho, Renato Abrantes Luna, and Vinicius Almeida de Oliveira.
    • Oncologic Surgeon of the Gaffreé and Guinle University Hospital, Rio de Janeiro.. guilhermeravanini@gmail.com.
    • Nutr Hosp. 2015 Aug 1; 32 (2): 953-7.

    Backgroundthis study aims to assess the organic inflammatory response of the video laparoscopic cholecystectomy, with abbreviation of the preoperative fasting to 2h using a carbohydrate and protein enriched solution.Methodsthis is a randomized, prospective study with patients divided into the following 2 groups: group A, conventional fasting and group B, 2h abbreviated fasting with oral ingestion of a carbohydrate and protein solution. Serum glucose, insulin, interleukin 1, and TNF-α were mesasured before ingestion of the solution, during induction of anesthesia, and 4 h after the end of surgery.Resultsthirty-eight patients completed the study without presenting pulmonary complications associated with bronchoaspiration. The postoperative HOMA-IR variance was greater in group A (p = 0.001).Conclusionthe abbreviation of preoperative fasting for 2 h, using carbohydrate and protein enriched solutions, is safe, reduces insulin resistance, and does not increase the risk of bronchoaspiration.Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

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