• Cleve Clin J Med · Mar 2006

    Review

    The yin and yang of tumor necrosis factor inhibitors.

    • Leonard Calabrese.
    • Section of Clinical Immunology, Department of Rheumatic and Immunologic Disease, The Cleveland Clinic Foundation, OH 44195, USA. calabrl@ccf.org
    • Cleve Clin J Med. 2006 Mar 1; 73 (3): 251-6.

    AbstractTumor necrosis factor (TNF) inhibitors have proven highly effective against a number of autoimmune diseases but have been disappointing in treating others. An increase in the risk of Mycobacterium tuberculosis and other opportunistic infections has been noted in patients treated with these agents. If we use these drugs, we need to weigh their beneficial and adverse effects.

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