• B Magnaes.
• Department of Neurosurgery, Ullevål Hospital, Oslo University Hospital, Norway.
• Br J Neurosurg. 1989 Jan 1; 3 (6): 659-68.

AbstractThe cranial compartment contributed 37% and the spinal compartment 63% to the total compliance of the craniospinal space in the horizontal body position. In the erect position the values were almost reversed, the cranial compartment contributing 66% and the spinal compartment 34%. The total compliance was almost unaffected by body position. The pulsatile volume of cerebrospinal fluid (CSF) moving between the cranial and spinal compartments was about 1 ml in the horizontal position. The corresponding pulsatile change in cerebral blood volume was calculated to be 1.6 ml. A craniospinal block increased the intracranial pressure amplitude by 110% in the horizontal position. The volume of CSF moving between the cranial and spinal compartments when sitting up and lying down, was about 3 ml. The pulsatile and postural flow rate of CSF may reach about 200 ml/min. High CSF flow velocity may impair the protective coating of CSF around the brain and thus contribute to herniation.

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