• Zhongguo Zhong Xi Yi Jie He Za Zhi · Mar 2007

    Randomized Controlled Trial Multicenter Study

    [Clinical observation on effect of compound Shiwei Tablet in treating urinary tract infection].

    • Yong-li Zhan, Xiu-ying Li, and Sheng-xian Wu.
    • Department of Nephrology, Guang' anmen Hospital Affiliated to China Academy of Chinese Medical Sciences, Beijing. zhanyongli88@sina.com
    • Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Mar 1; 27 (3): 249-51.

    ObjectiveTo evaluate the safety and efficacy of Compound Shiwei Tablet (CST) in treating upper and lower urinary tract infection (UTI, pyretic stranguria of dampness-heat of the Lower-jiao type in 'TCM).MethodsA multi-center, randomized, and opened clinical trial was conducted in the UTI patients with Sanjin Tablet (ST) as the parallel positive control medicine. The comprehensive efficacy, effect on TCM syndrome score, and change of urinary leukocyte count were observed, and the adverse reaction was recorded.ResultsIn the 147 upper UTI cases and the 312 lower UTI cases after treatment, the comprehensive effect was higher and urinary leukocyte was less in the CST treated patients than in the ST treated patients (P < 0.05); but significant difference in the improvement of TCM symptoms was found between them only in the lower UTI cases ( P < 0.05); and no adverse reaction was observed during the treatment course.ConclusionCST has definite therapeutic efficacy on UTI and is safe in clinical application.

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