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Med Sci Sports Exerc · Jun 2006
Randomized Controlled Trial Comparative StudyOxidative stress response to aerobic exercise: comparison of antioxidant supplements.
- Richard J Bloomer, Allan H Goldfarb, and Michael J McKenzie.
- Department of Health and Sport Sciences, University of Memphis, Memphis, TN 38512, USA. rbloomer@memphis.edu
- Med Sci Sports Exerc. 2006 Jun 1; 38 (6): 1098-105.
PurposeTo compare the effects of two antioxidant formulas on biomarkers of oxidative stress before and after aerobic exercise.MethodsAerobically trained men (N=25) and women (N=23) were assigned to one of three treatments: 400 IU of vitamin E+1 g of vitamin C (V; N=15), a fruit and vegetable juice powder concentrate (FV; N=16), or a placebo (P; N=17). Subjects ran for 30 min at 80% VO(2 max) before, after 2 wk of supplementation, and after a 1-wk washout period. Blood samples were taken before and immediately after exercise and analyzed for protein carbonyls (PC), malondialdehyde (MDA), 8-hydroxydeoxyguanosine (8-OHdG), and vitamins C and E.ResultsThe V treatment increased plasma vitamin C and E after 2 wk (P
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