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The Journal of pediatrics · Aug 2003
Case ReportsSerum alpha-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia.
- Carol L Clericuzio, Emily Chen, Dawn Elizabeth McNeil, Timothy O'Connor, Elaine H Zackai, Livija Medne, Gail Tomlinson, and Michael DeBaun.
- Department of Pediatrics, University of New Mexico, ACC-3, Albuquerque, NM 87131, USA.
- J. Pediatr. 2003 Aug 1; 143 (2): 270-2.
AbstractAn elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum alpha-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.
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