• Mymensingh Med J · Jan 2009

    Correlation between helicobacter pylori and gastric diseases: a study in King Fahad Hospital at Al-Baha of Saudi Arabia.

    • Kamrul Hasan Khan, Masuda Begum, Mounzer Saleh, and Moshiur Rahman Khasru.
    • Department of Pathology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh. kmrlcrts@bdcom.com
    • Mymensingh Med J. 2009 Jan 1; 18 (1 Suppl): S113-118.

    AbstractHelicobacter pylori (H. pylori) infection is a common and significant public health problem. About 70-90% of the population in developing countries and 25-50% in developed countries were infected with H. pylori. Many studies have been undertaken concerning the role of H. pylori in the etiopathogenesis of chronic gastritis and peptic ulcer, as well as its role in the development of stomach malignancies. The objective of the present study was to find out the correlation between helicobacter pylori and gastric diseases among the Saudi population. This retrospective study was conducted at King Fahad Hospital at Al-Baha of Saudi Arabia between 1st January and 31st December 2004. Patients presented with gastrointestinal symptoms attending at hospital were included in the study. Gastric biopsy specimens were obtained from 187 patients with different type of gastroduodenal diseases. Histopathological study of gastric biopsy was carried out in the laboratory of the same hospital. Grades of H. pylori density in specimens in the present study was classified according to Sydney classification. Total 187 patients were included in the present study. There age range was 06-98 years and 108 were male and 79 were female. Maximum 30.5% patients were belonged to above 60 years age group. Out of all respondents maximum 86.6% patients had gastritis followed by 6.4% had normal histopathological finding, 3.7% had non specific findings and 3.2% had malignancy. Positive correlation was observed between severity of gastritis and grading of H. pylori load. (r=+0.382; p value <0.001). The findings of the present study reveal that H. Pylori is responsible for many gastric diseases. It was also concluded from the study that severity of gastritis associated with H. Pylori increases with the heavy load of infection. To confirm the association prospective study with large sample size is recommended.

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