• Mayo Clinic proceedings · Jun 1996

    Case Reports

    Endobronchial thrombolysis with streptokinase for airway obstruction due to blood clots.

    • Z Vajo and J M Parish.
    • Department of Medicine, Maricopa Medical Center, Phoenix, Arizona 85008, USA.
    • Mayo Clin. Proc. 1996 Jun 1; 71 (6): 595-6.

    AbstractTo our knowledge, only four reports have previously described endobronchial thrombolysis with streptokinase for airway obstruction due to blood clots; the highest dose used was 80,000 U. Herein we describe a 21-year-old woman with pulmonary embolism who experienced life-threatening airway obstruction due to a large blood clot in the distal trachea. Streptokinase (120,000 U), injected through a fiberoptic bronchoscope, partially dissolved the clot. The rest of the clot was removed easily with forceps and suctioning. No complications occurred.

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