• Nippon Rinsho · Oct 2015

    [Diabetes-related osteoporosis].

    • Ippei Kanazawa.
    • Nippon Rinsho. 2015 Oct 1; 73 (10): 1718-22.

    AbstractAccumulating evidence has shown that the risk of osteoporotic fracture is increased in patients with type 1 and 2 diabetes mellitus. Measurement of bone mineral density is not a good evaluation tool for diabetes-related osteoporosis because the underlying mechanism is based on the deterioration of bone quality with accumulation of collagen cross-links of advanced glycation end products, decreased bone formation, and cortical porosity. Thus, we should choose the anti-osteoporosis drug while taking the mechanism into consideration. However, the evidence of treatments for diabetes-related osteoporosis is not sufficient so far. Therefore, further studies are necessary to solve this issue in future.

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