• Hematol. Oncol. Clin. North Am. · Feb 2015

    Review

    A critical look at local-regional management of peritoneal metastasis.

    • Carlos H F Chan, James C Cusack, and David P Ryan.
    • Division of Surgical Oncology, Massachusetts General Hospital Cancer Center, Yawkey 7B, 55 Fruit Street, Boston, MA 02114, USA.
    • Hematol. Oncol. Clin. North Am. 2015 Feb 1; 29 (1): 153-8.

    AbstractFor patients with stage IV colorectal cancer, the presence of peritoneal metastases is a poor prognostic feature. Despite the improvement in systemic therapy, long-term survival remains poor for patients with peritoneal carcinomatosis. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) can be associated with long-term survival in patients who have limited peritoneal disease, particularly those who can have complete cytoreduction. Whether the possible benefit of CRS and HIPEC is from the surgical resection of all disease or the combination of CRS and HIPEC remains unclear. Copyright © 2015 Elsevier Inc. All rights reserved.

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