• Dermatologic clinics · Jul 2006

    Review

    Drug-induced nail diseases.

    • Bianca Maria Piraccini, Matilde Iorizzo, Michela Starace, and Antonella Tosti.
    • Department of Dermatology, University of Bologna, Via Massarenti, 1-40138 Bologna, Italy. bmpiracc@med.unibo.it
    • Dermatol Clin. 2006 Jul 1; 24 (3): 387-91.

    AbstractAlthough many nail disorders have been associated with drug intake, most reports are anecdotal. Most nail changes caused by drugs are the outcome of acute toxicity to the nail epithelia; nail symptoms depend on which nail structure is damaged. The most com-mon symptoms include Beau's lines/onychomadesis, melanonychia, onycholysis, and periungual pyogenic granulomas. Drug-induced nail abnormalities are usually transitory and disappear with drug withdrawal, but sometimes persist over time. This article reviews drugs that have been consistently associated with nail abnormalities.

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