• Clin Adv Hematol Oncol · Dec 2003

    Review

    Antiphospholipid antibodies.

    • Douglas A Triplett.
    • Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. dtriplett@chs.cami3.com
    • Clin Adv Hematol Oncol. 2003 Dec 1; 1 (12): 726-30.

    AbstractAntiphospholipid antibodies (APAs) have been associated with thromboembolic events. Since they were fi rst described in 1906, APAs have been the subject of multidisciplinary studies seeking to link them to potential pathophysiologic mechanisms. This review summarizes the different types of APAs, antigenic targets, clinical complications associated with APAs, and APA syndrome. In addition, the currently available methods for laboratory identification of lupus anticoagulants are discussed, as is the laboratory diagnosis of anticardiolipin antibodies.

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