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Dermatologic clinics · Jan 2016
ReviewRandomized Controlled Trials for the Treatment of Hidradenitis Suppurativa.
- Dominique C van Rappard, Jan R Mekkes, and Thrasivoulos Tzellos.
- Department of Dermatology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands. Electronic address: d.c.vanrappard@amc.uva.nl.
- Dermatol Clin. 2016 Jan 1; 34 (1): 69-80.
AbstractHidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent, debilitating skin disease. Several treatment modalities are available, but most of them lack high-quality evidence. A systematic search was performed to identify all randomized controlled trials for the treatment of HS in order to review and evaluate the evidence. Recommendations for future randomized controlled trials include using validated scores, inclusion of patient rated outcomes, and thorough report of side effects. Evidence for long-term treatment and benefit/risk ratio of available treatment modalities is needed in order to enhance evidence-based treatment in daily clinical practice. Combining surgery with antiinflammatory treatment warrants further investigation. Copyright © 2016 Elsevier Inc. All rights reserved.
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