• Asian Cardiovasc Thorac Ann · Apr 2009

    Short- and long-term results of lung resection for cancer in octogenarians.

    • Luca Voltolini, Cristian Rapicetta, Tommaso Ligabue, Luca Luzzi, Valerio Scala, and Giuseppe Gotti.
    • Thoracic Surgery Unit, University Hospital of Sienna, Siena, Italy.
    • Asian Cardiovasc Thorac Ann. 2009 Apr 1; 17 (2): 147-52.

    AbstractTo analyze short- and long-term results of surgery in octogenarians, we reviewed data of 96 consecutive patients aged 80 years or more who were operated on for non-small-cell lung carcinoma from 1990 to 2005. Risk factors for complications, perioperative mortality, and long-term survival were assessed by univariate and multivariate analysis. Major complications developed in 17 (17.7%) patients, leading to death in 9 (9.4%) of them. Resection of more than 1 lobe, cardiorespiratory comorbidity, PaO2 < 75 mm Hg, and CO diffusion capacity <60% were predictive of major complications; extended resection was also predictive of 30-day mortality. The overall 5-year survival rate was 38%, with a significant difference between stage I/II and stage III. In multivariate analysis only pathological stage was related to long-term survival. Surgery is feasible for octogenarians, and even patients in stage II can achieve remarkable survival.

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