• Annales de chirurgie · Jan 1995

    [Intraoperative radiotherapy. Preliminary results].

    • P Maingon, J Fraisse, O Brun, S Salas, S Naudy, A Bernard, P Goudet, J L Chalencon, C Minello, and M Pillet.
    • Service de Radiothérapie, Centre Georges-François-Leclerc, Dijon.
    • Ann Chir. 1995 Jan 1; 49 (4): 305-9.

    AbstractWe report a series of 40 patients treated by intraoperative radiotherapy between 1988 and 1992 (18 primary tumors, 13 local recurrences and 9 nodal extensions). The doses delivered were 15 Gy to 25 Gy, completed by external radiotherapy (15 to 45 Gy) in 13 cases. The local tumor control rate was 61% for initial therapy in primary tumors (70% for adenocarcinoma of the stomach) and 80.9% after complete en bloc surgery. The local control rate after palliative surgery for local recurrences is 38% and 33% for nodal extension. Two patients died (5%) during the postoperative period. We observed 2 hemorrhages and 3 cases of stone-free cholecystitis. The value of this approach must be confirmed in rigorous indications in comparison with surgery alone in controlled and randomised clinical trials.

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