• Christian Dupont, Hervé Gouya, Rozy Panzo, Dominique Hubert, Jean-Michel Correas, Line Agrario, Jeanne Chapron, Isabelle Honoré, Reem Kanaan, Paul Legmann, Daniel Dusser, Olivier Vignaux, and Pierre-Régis Burgel.
• 2 Université Paris Descartes, Sorbonne Paris Cité, Paris - France.
• J Vasc Access. 2015 May 1; 16 (3): 245-9.

BackgroundPeripherally inserted central catheters (PICCs) are increasingly used in patients with cystic fibrosis (CF) or with non-CF bronchiectasis, but little data exist on catheter-related complications in this setting.MethodsProspective follow-up of consecutive PICCs inserted for intravenous (IV) antibiotics in adults with CF or with non-CF bronchiectasis at Cochin Hospital (Paris, France).ResultsBetween March 2009 and December 2011, 182 PICCs were prescribed in 117 adults (67 CF and 50 non-CF patients). Ultrasound-guided placement of catheter was successful in 174/182 (95.6%) procedures; no insertion complication occurred. The mean ± SD catheter dwell time was 15 ± 9 days. No catheter-associated bloodstream infection occurred; main complications were symptomatic upper limb deep vein thrombosis (2%), catheter obstruction (18%) and persistent pain after catheter insertion (18%). Patients' satisfaction was high and PICC could be used to perform antibiotic courses in most patients.ConclusionsPICCs were generally safe for performing IV antibiotic courses in patients with CF or non-CF bronchiectasis, but prolonged pain and/or catheter obstruction occurred in approximately 20% of cases.

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