• Kazuhisa Takeda, Takafumi Kumamoto, Kazunori Nojiri, Ryutaro Mori, Koichi Taniguchi, Ryusei Matsuyama, Kuniya Tanaka, and Itaru Endo.
• Hepato Gastroenterol. 2015 May 1; 62 (139): 693-7.

Background/AimsStroke volume variation (SVV) is a sensitive, functional preload index for evaluating responsiveness to volume loading in patients during liver transplantation (LT). However, there have been few reports concerning the experience of using SVV after LT.MethodologyOf 61 patients who underwent living donor LT (LDLT) at our institute, we used only central venous pressure (CVP) to guide fluid management in the first 52 patients (conventional group) and used both SVV and CVP in the next 9 patients (SVV group). The boundary values used for fluid management were 10mmHg for CVP and 10% for SVV. Changes in SVV and CVP were compared.ResultsIn the SVV group, SVV was less than 10% in all patients when the diuretic phase appeared. However, CVP was more than 10mmHg in only 4 cases (44.4%). Between surgery and the removal of endotracheal tubes, the lowest the ratio between arterial oxygen tension and fractional inspired oxygen (PaO2/FiO2 ratio) in the SVV group (290.7 ± 100.5) was significantly higher than that in the conventional group (205.6 ± 98.9, P = 0.017).ConclusionPostoperative fluid management using SVV may be especially useful after LDLT. Monitoring the circulating blood volume using a 10% SVV index is useful for avoiding lung edema after LT.

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