Hepato Gastroenterol
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Hepato Gastroenterol · May 2015
Comparative StudyStroke Volume Variation for the Evaluation of Circulating Blood Volume after Living Donor Liver Transplantation.
Stroke volume variation (SVV) is a sensitive, functional preload index for evaluating responsiveness to volume loading in patients during liver transplantation (LT). However, there have been few reports concerning the experience of using SVV after LT. ⋯ Postoperative fluid management using SVV may be especially useful after LDLT. Monitoring the circulating blood volume using a 10% SVV index is useful for avoiding lung edema after LT.
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Hepato Gastroenterol · May 2015
Planning Sonography Using Real-time Virtual Sonography and Contrast-enhanced Sonography for Radiofrequency Ablation of Inconspicuous Hepatocellular Carcinoma Nodules.
Determining whether planning sonography, using real-time virtual sonography (RVS) and contrast-enhanced sonography (CEUS), enables the identification of inconspicuous HCC nodules on conventional sonography (US), during percutaneous radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC). ⋯ This study suggested that planning US using RVS and CEUS permits the identification of most inconspicuous HCC nodules, thereby improving the success rate of RFA.
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Hepato Gastroenterol · May 2015
ReviewMystery Story about Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) are Disguised?
In this review we would like to focus our attention upon very controversial reports on Erythropoietin (Epo) and Erythropoietin Receptor (EpoR) expression in cancer patients. The effects of Epo on cancerous tissues are poorly understood. Hypoxia results in an increase in the level of the production of both Epo and EpoR via activation of the hypoxia-inducible factor 1 (HIF-1) pathway. ⋯ Macrophages stimulate vessel sprouting via a soluble factor other than VEGF, rather than through direct contact with endothelial cells. The intriguing questions are set about many researches to link Epo/EpoR expression and function in order to establish one of the mechanisms of tumor growth, disease progression of cancer patient. However, it is uncertain role in tumour angiogenesis as promoter and stimulator of tumour growth which should need to be furtherly validated.
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Hepato Gastroenterol · May 2015
Clinical Features of Surgical Resection for Liver Metastasis from Extremity Soft Tissue Sarcoma.
The aim of the present study was to define the prognostic factors for survival after hepatic metastasectomy from extremity soft tissue sarcoma. ⋯ Hepatic metastasectomy for extremity soft tissue sarcoma can be associated with prolonged survival. Complete resection, longer disease-free interval, no tumor recurrence before liver resection and repeated resection for recurrent liver metastases are the most predictive factors for prolonged survival.
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Hepato Gastroenterol · May 2015
Decreased Expression of MIR-134 and its Clinical Significance in Human Colorectal Cancer.
Dysregulation of miRNA is always associated with cancer development and progression. Aberrant expression of miR-134 has been found in some types of cancer. However, miR-134 expression and its clinical significance in colorectal cancer (CRC) have not been explored. The aim of this study was to explore the effects of miR-134 in CRC tumorigenesis and development. ⋯ These findings indicate that miR 134 may act as a tumor suppressor in CRC and would serve as a novel therapeutic agent for miR-based therapy.