• Adarsh S Kadoor, Kruti Patel, Brittany N Burton, and Rodney A Gabriel.
• School of Medicine, University of California, San Diego (9500 Gilman Dr), La Jolla, CA 92093, USA). Electronic address: akadoor@health.ucsd.edu.
• J Clin Anesth. 2021 Dec 1; 75: 110472.

ImportanceRising rates of obesity and outpatient performance of parathyroidectomies are making it increasingly crucial to investigate the association of obesity with post-operative complications.ObjectiveTo determine whether Class 3 obesity is associated with increased same-day admission compared to lower obesity classes following outpatient parathyroidectomy.DesignRetrospective cohort study.SettingOutpatient surgery.Patients12,973 patients ≥18 years old who underwent outpatient parathyroidectomy between 2014 and 2016, per the American College of Surgeons National Surgical Quality Improvement Program registry.InterventionsPrimary exposure variable: body mass index (BMI), with patients assigned to one of six cohorts.MeasurementsPrimary outcome measure: same-day admission. Secondary outcome measure: 30-day readmission. Logistic regression was used to calculate odds ratios (OR) and 95% confidence intervals (CI).Main ResultsThere was a final sample size of 12,973 adult patients who underwent parathyroidectomy from 2014 to 2016. The admission rate for BMI ≥30 and < 40 kg/m2 (reference cohort) was 42.6%. The admission rates for Class 3 obesity categories were 46.2%, 56.2%, and 52.6% for those in the BMI range of ≥40 kg/m2 and < 50 kg/m2, ≥50 kg/m2 and < 60 kg/m2, and ≥ 60 kg/m2, respectively. On multivariable logistic regression, there were no difference in the odds of 30-day hospital admission or readmission rate with any of the BMI cohorts when compared to the reference group.ConclusionsThere is no significant difference in rates of same-day admission or 30-day readmission between any Class 3 (BMI ≥40 kg/m2) obesity cohort and the Class 1 and 2 (BMI ≥30 and < 40 kg/m2) reference cohort following outpatient parathyroidectomy. This corroborates the notion that BMI classes cannot be used in a vacuum to determine eligibility for outpatient parathyroidectomy - a concept that can guide safe and cost-effective institutional practices.Copyright © 2021 Elsevier Inc. All rights reserved.

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