• Pol. Arch. Med. Wewn. · Nov 2021

    Outcomes of COVID-19 in hospitalized kidney and liver transplant recipients- a single-center experience.

    • Aleksander Ślusarczyk, Adam Tracz, Magdalena Gronkiewicz, Lidia Jureczko, and Teresa Bączkowska.
    • Department of Transplantation Medicine and Nephrology, Medical University of Warsaw, Warsaw, Poland; Department of General, Oncological and Functional Urology, Medical University of Warsaw, Warsaw, Poland. slusarczyk.aleksander@gmail.com
    • Pol. Arch. Med. Wewn. 2021 Nov 30; 131 (11).

    AbstractIntroduction: Solid organ transplant recipients seem to be more susceptible to severe COVID-19. Objectives: Our study aimed to assess the clinical outcomes of COVID-19 in kidney (KTRs) and liver transplant recipients (LTRs). Patients and methods: In this single-center study, the medical records of KTRs and LTRs with PCR-confirmed COVID-19 admitted between November 9, 2020 and February 26, 2021 were retrospectively reviewed. Results: Overall, 41 patients, including 32 KTRs (78%), one kidney-pancreas transplant recipient (2.4%), and 8 LTRs (19.5%) were included. Seven patients (17%) experienced COVID-19 in the first month after transplantation. Among the KTRs, 72% were male and the median (interquartile range) age was 54 (47–62) years. During a median (interquartile range) of 12 (8–18) days of hospital stay, 72.7% of the KTRs experienced acute kidney injury, 45.5% developed acute respiratory distress syndrome (ARDS), and 30.3% died. Baseline estimated glomerular filtration rate, respiratory rate on admission, and diabetes mellitus constituted independent risk factors for in-hospital mortality in the KTRs. The LTRs experienced relatively mild COVID-19: only 2 patients (25%) required oxygen supplementation and a single patient (12.5%) died of severe ARDS. Conclusion: In summary, hospitalized KTRs with COVID-19 are at a high risk of acute kidney injury, ARDS, and death.

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