• Clinical imaging · Apr 1995

    Case Reports

    Squamous cell carcinoma of the thymus with paraneoplastic hypercalcemia.

    • J M Negron-Soto and P N Cascade.
    • Department of Pathology, University of Chicago Hospitals, Illinois, USA.
    • Clin Imaging. 1995 Apr 1; 19 (2): 122-4.

    AbstractPrimary thymic carcinoma is a rare neoplasm that in contradistinction to thymoma, is not supposed to be associated with a paraneoplastic syndrome. A 73-year-old man, with new onset of disorientation, was found to have an elevated serum calcium level as the cause. Computed tomography demonstrated a mediastinal mass, pericardial invasion, and metastases to the lung. Examination of a biopsy specimen revealed thymic squamous cell carcinoma. Thus, a paraneoplastic syndrome, in this case hypercalcemia, does not exclude primary carcinoma of the thymus.

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