• H K Eltzschig, R Darsow, T H Schroeder, H Hettesheimer, and H Guggenberger.
• Department of Anaesthesiology, Eberhard-Karls-University of Tübingen, Tübingen, Germany. heltzschig@partners.org
• J Clin Anesth. 2001 Jun 1;13(4):264-7.

Study ObjectivesTo study the effect of tracheal intubation or laryngeal mask airway (LMA) insertion on intraocular pressure (IOP) in strabismus patients undergoing balanced anesthesia with sevoflurane and remifentanil.DesignOpen, prospective, randomized study.SettingTertiary care academic medical institution.Patients40 adult ASA physical status I and II patients scheduled for elective strabismus surgery.InterventionPatients were randomized to receive either tracheal intubation or LMA insertion following mask induction with sevoflurane in combination with IV remifentanil.MeasurementsIntraocular pressure, mean arterial pressure (MAP), and heart rate (HR) were measured before induction, immediately following induction, and after airway insertion.Main ResultsIntraocular pressure after tracheal intubation or LMA insertion did not differ significantly from preoperative baseline values. Mean arterial pressure and HR did not significantly differ between groups at any time point.ConclusionsRemifentanil and sevoflurane are not associated with an increase in IOP response during tracheal intubation or LMA insertion above baseline in healthy patients undergoing ophthalmic surgery.

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