• Minerva ginecologica · Oct 2007

    Comparative Study

    [Endometrial ablation versus hysterectomy in women treated with tamoxifen].

    • I Capuano, A Caporale, P Vagnetti, A Di Domenico, M Felicetti, M Torella, and A L Borrelli.
    • Dipartimento di Scienze Ginecologiche Ostetriche e della Riproduzione, Seconda Università degli Studi di Napoli, Napoli, Italy.
    • Minerva Ginecol. 2007 Oct 1; 59 (5): 499-504.

    AimThe aim of our study is the assessment of the importance of the endometrial ablation versus hysterectomy in patients treated with tamoxifen for previous breast cancer.MethodsFifty-eight outpatients in therapy with tamoxifen for 1 year were controlled in the Department of Gynaecology of the University of Naples. We have selected these patients in two groups: group A, with 28 women with abnormal uterine bleeding and endometrial thickness >8 mm and group B, with 30 normal endometrium asymptomatic women. All patient of group A and 18 of group B were treated with endometrial ablation.ResultsNext follow-up showed normal hysteroscopy figures in 89% of cases and 5% of cases needed a hysterectomy for new abnormal uterine bleeding and cytology.ConclusionOur results show the utility of endometrial ablation especially in selected cases in therapy with tamoxifen for previous breast cancer.

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