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- Yueqi Wang, Minggang Su, and Lin Li.
- Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, China.
- Medicine (Baltimore). 2019 Oct 1; 98 (41): e17446.
RationaleThe infiltration of tumor cells to pulmonary lymphatic system, as known as pulmonary lymphangitis carcinomatosis (PLC), is a rare presentation of pulmonary metastases.Patient ConcernsWe reported a case of a 66-year-old man after surgery, chemotherapy, and radiation therapy for colon cancer. Two months after these therapies, the patient complained of nonproductive cough for 1 week.Diagnoses18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) scanning revealed increased FDG uptake along the thickened bronchovascular bundles, in bilaterally scattered ground-glass opacities and in mediastinal lymphadenopathy. The transbronchial biopsy and pathological study confirmed the diagnosis of PLC.InterventionsAntineoplastic treatment (cetuximab) were administered after the patient was diagnosed with PLC.OutcomesThe patient died of respiratory failure within 3 months after the onset of his symptom.Lessons18F-FDG PET/CT play an important role in identifying PLC, in selecting possible biopsy sites, and in accessing the extent of metastatic disease.
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