• Neurol. Sci. · Jan 2020

    Association between fatigue and motor progression in Parkinson's disease in southern Chinese.

    • Hong-Xiang Yu, Meng-Ruo Guo, Gang Li, and Bei Zhang.
    • Department of Neurology, East Hospital, Tongji University School of Medicine, 1800 Yuntai Road, Shanghai, 200123, China.
    • Neurol. Sci. 2020 Jan 1; 41 (1): 161-164.

    Study ObjectivesThe aim was to investigate whether fatigue could predict the development of motor symptoms of Parkinson's disease (PD) in a southern Chinese population.MethodsIn total, 246 PD patients were recruited. All patients were evaluated by Fatigue Severity Scale (FSS), Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, and Unified PD Rating Scale provided by Movement Disorders Society (MDS-UPDRS). MDS-UPDRS was re-evaluated after 2 years.ResultsFSS scores were associated with total score and subparts of MDS-UPDRS (total: p 0.039, p 0.030, adjusted; part III: p 0.022, p 0.016, adjusted).ConclusionsThe symptom of subjective fatigue could predict the progression of PD.

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