• Semin Cutan Med Surg · Jun 2000

    Review

    Mycosis fungoides: classic disease and variant presentations.

    • M S Howard and B R Smoller.
    • Department of Pathology, University of Arkansas for Medical Sciences, Little Rock 72205, USA.
    • Semin Cutan Med Surg. 2000 Jun 1; 19 (2): 91-9.

    AbstractMycosis fungoides is a peripheral non-Hodgkin's T-cell neoplastic process, representing the most common type of primary cutaneous malignant lymphoma. Neoplastic lesions classically show skin predilection and characteristic clinical and histologic features in patch, plaque, and tumor stages. In addition, several clinicopathologic variants of mycosis fungoides have been delineated, including poikiloderma atrophicans vasculare (parapsoriasis variegata), Sézary syndrome, granulomatous mycosis fungoides, hypopigmented mycosis fungoides, folliculocentric mycosis fungoides, syringotropic mycosis fungoides, and Woringer Kolopp disease. We will review the salient features of patch, plaque, and tumor stage mycosis fungoides in this article and follow with a discussion of these variant clinicopathologic presentations and of therapeutic modalities.

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