• Curēus · Sep 2019

    Correlation of Optic Nerve Sheath Diameter with Direct Measurement of Intracranial Pressure through an External Ventricular Drain.

    • M Asghar Ali, Madiha Hashmi, Shahzad Shamim, Basit Salam, Sheema Siraj, and Bushra Salim.
    • Anaesthesiology, Aga Khan University Hospital, Karachi, PAK.
    • Cureus. 2019 Sep 26; 11 (9): e5777.

    AbstractBackground Early diagnosis and management of raised intracranial pressure (ICP) is essential for preventing brain damage and even death. Invasive monitoring is the gold standard to measure raised ICP but it may not be feasible in a heterogeneous group of patients. Noninvasively, a simple bedside ocular ultrasound can detect elevated ICP. The aim of our study was to evaluate the correlation between optic nerve sheath diameter (ONSD) and direct ICP measurements and to determine sensitivity and specificity of ONSD measurements to detect elevated ICP (>15 cm H2O). Methods This prospective study was conducted at the intensive care unit/high dependency units/wards of Aga Khan University Hospital. Patients with external ventricular drain (EVD) for intracranial hypertension were enrolled. Ocular ultrasound was performed with a 7.5 MHz linear probe. For each subject, three measurements on each eye were performed and the mean of the six measurements was determined. EVD was temporarily occluded and the ICP was recorded every minute for five minutes. A receiver operative characteristics (ROC) curve was constructed to determine the optimal ONSD cutoff to detect ICP above 15 cm H2O. Results A total of 35 adult patients were included in this study. The ONSD was linearly correlated with ICP in both right and left eyes (r = 0.662, p = 0.0005 and r = 0.449; p < 0.002) respectively. Pearson correlation of ONSD between two eyes (right and left) was 0.749; p = 0.0005 and 0.726; p = 0.005 at day 1 and day 2, respectively. ROC curve was created and observed that AUC of right and left eyes was 0.815 (95% CI: 0.61 to 0.99) and 0.69 (95% CI: 0.37 to 0.99). Conclusion According to this study, ventriculostomy measurements of ICP are directly correlated with ultrasound ONSD measurements. Hence, we conclude that ONSD measured by ocular ultrasound is a simple yet effective method to detect raised ICP.Copyright © 2019, Ali et al.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…