• Br J Anaesth · Apr 1980

    Randomized Controlled Trial Comparative Study Clinical Trial

    Comparison of carbonated bupivacaine and bupivacaine hydrochloride for extradural anaesthesia.

    • D T Brown, D H Morison, B G Covino, and D B Scott.
    • Br J Anaesth. 1980 Apr 1; 52 (4): 419-22.

    AbstractA double-blind comparison of carbonated bupivacaine and bupivacaine hydrochloride in extradural anaesthesia was performed in 40 patients. No significant differences in the onset times, sensory blockade, motor blockade and duration of anaesthesia were demonstrated. Carbonated bupivacaine does not appear to offer any advantage over the hydrochloride salt for extradural anaesthesia.

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